When it comes to treating erectile dysfunction (ED), several options are available. Common medications include tadalafil, testosterone, avanafil, and vardenafil. The first step is to consult a licensed medical professional to obtain a prescription.
While numerous medications, supplements, and herbal remedies claim to enhance testosterone levels and libido, they might not be the ideal solution for everyone. If you’ve been grappling with bedroom performance issues, you might be tempted by these alternatives.
However, sexual health encompasses more than just endurance and performance. When individuals face difficulty achieving an erection, many of these products, despite their impressive assertions, often fall short, particularly when a direct and scientifically-backed approach is required for conditions like erectile dysfunction.
Dr. Blen Tesfu, a general practitioner, concurs. “Turning to natural or herbal supplements for ED is understandable,” she notes. “Yet, it’s vital to recognize that these supplements lack the same FDA regulation as prescription medications. This means their safety, effectiveness, and accuracy in labeling can’t be assured. Moreover, some supplements might have negative interactions with other medications.”
Here, we dissect seven top ED medications, providing comprehensive information on their usage.
The 7 Most Common Types of Erectile Dysfunction Medications
Here are the top seven types of ED medications:
- alprostadil
- avanafil
- sildenafil
- tadalafil
- testosterone
- vardenafil
- vitamins and supplements
Understanding Erectile Dysfunction
Erectile dysfunction (ED) occurs when someone struggles to achieve or maintain a firm erection during sexual activity or loses it prematurely.
According to Linda Khoshaba, NMD, FABNE, and founder of Natural Endocrinology Specialists (NES), ED is “the inability to achieve or maintain an erection sufficient for satisfactory sexual performance.” Khoshaba, an experienced naturopathic endocrinologist, has identified various factors contributing to ED, including diabetes, heart diseases, hormonal imbalances, and psychological concerns. Occasionally losing an erection is normal and not a major worry. However, if it happens frequently over 4 weeks or more, it could be a sign of ED.
Contrary to popular belief, ED isn’t limited to older men. It also affects younger males, and it’s more common than realized. The Urology Care Foundation estimates that about 30 million men in the United States experience this condition. ED arises from a blend of physical and psychological factors. Consulting a doctor is vital to identifying the potential causes and devising a suitable treatment plan.
Many find that adjusting their daily routine can alleviate ED symptoms. This might involve dietary changes, talk therapy, or using ED medications.
Understanding the Causes of Erectile Dysfunction
Not everyone with ED requires medication. It’s important to comprehend the underlying cause before considering medication.
If you suspect ED, consult your primary care doctor. They’ll perform a physical examination, conduct specific lab tests, and assess your comprehensive medical and psychosocial history. “Erectile dysfunction can stem from various factors, physical and psychological,” says Blen Tesfu, MD. “Common physical triggers include heart disease, high cholesterol, high blood pressure, diabetes, obesity, tobacco use, alcohol, and certain prescription medications.”
Depending on the exam and evaluation, a doctor might refer you to a mental health professional to address performance anxiety or relationship issues associated with ED.
Root Causes of Erectile Dysfunction
Erectile dysfunction (ED) can stem from untreated conditions like diabetes or high blood pressure. Addressing these issues may alleviate your ED symptoms.
Medication-Induced ED
Certain medications you take might lead to ED. These could include drugs for:
- High blood pressure
- Heart disease
- Depression
- Seizures
- Cancer
Consult your doctor to assess your current medications and explore adjustments that could enhance your ED situation.
Other Contributing Factors
Several factors can contribute to ED. Embracing habits that support overall health can help alleviate symptoms.
“Maintaining a healthy weight, engaging in regular physical activity, limiting alcohol, avoiding tobacco and illicit substances, and managing stress can all contribute to better erectile function,” states Tesfu.
Consider reducing or quitting smoking, maintaining a moderate weight, exercising regularly, and moderating alcohol consumption to improve your condition.
How Do Erectile Dysfunction Medications Function?
Erectile dysfunction (ED) often arises from limited blood flow to the penis. When sexually aroused, insufficient blood flow hampers the ability to achieve and maintain an erection.
ED medications operate by counteracting or reducing the factors that hinder this blood flow. A common category of these medications is PDE5 inhibitors. PDE5, or phosphodiesterase type 5, is an enzyme that accumulates over time, impeding normal blood circulation to and from the penis. PDE5 inhibitors temporarily mitigate the effects of PDE5, facilitating easier erection.
“These medications enhance the effects of nitric oxide, a natural compound that relaxes penile muscles, boosts blood flow, and facilitates erection during sexual arousal,” explains Khoshaba. Unconventional treatments prioritize heart health and blood pressure enhancement to mitigate ED symptoms.
If traditional PDE5 inhibitors prove ineffective, your doctor may explore alternative treatments, as ED can be an early sign of serious conditions like diabetes or heart disease. We’ve compiled a list of common ED medications and their effectiveness for those seeking ED treatment options.
Comparison of Popular ED Medications
Alprostadil
Alprostadil (Caverject, Edex, MUSE) is available as an injectable solution or a penile suppository.
Inject the solution directly into the penis 5 to 20 minutes before intercourse. You can use it up to three times weekly, with a minimum 24-hour gap between injections.
With MUSE (Medicated Urethral System for Erections), administer the suppository 5 to 10 minutes before sex, limiting use to twice within 24 hours.
Price of Alprostadil
Currently, only brand-name versions of alprostadil are available, resulting in a higher cost than generic alternatives for other ED medications.
GoodRx says the average retail price for two 10 mcg cartridges is approximately $180.
Alprostadil Side Effects
Alprostadil may lead to these common side effects:
- Penile and testicular pain
- Burning sensation in the urethra
Avanafil
Avanafil, branded as Stendra, is a PDE5 inhibitor taken orally. Consume it approximately 15 minutes before sexual activity, but remember not to take it more than once daily. Avoid PDE5 inhibitors if you use nitrates for heart conditions, such as isosorbide mononitrate (Monoket) and nitroglycerin (Nitrostat). Combining nitrates with avanafil could lead to dangerous drops in blood pressure and even fatal outcomes.
Price for avanafil
Avanafil is presently exclusively available under the brand Stendra. As a brand-name medication, it generally costs more than comparable generic options.
The price of avanafil varies depending on the pharmacy, with retail prices typically ranging from $320 to $405 for six 200 mg tablets, as per GoodRx.
Common avanafil side effects
⦁ Headache
⦁ Facial flushing and warmth
⦁ Stuffy or runny nose
⦁ Back pain
⦁ Sore throat
Sildenafil
Introduced in 1998 as the pioneer PDE5 inhibitor, sildenafil, or Viagra, remains one of the most recognized ED treatments.
Viagra is available solely as an oral tablet and various cost-effective generic versions of the medication are accessible. It should be taken as needed once a day. Allow around 30 minutes for it to become effective, taking it roughly an hour before sexual activity for optimal results.
Price for sildenafil
Sildenafil is a wallet-friendly choice for managing erectile dysfunction, particularly due to online platforms like Roman and Hims. Its affordability remains noteworthy, even without insurance.
Sometimes, generic sildenafil can cost as low as $2 per pill from select providers.
Common sildenafil side effects
⦁ Headache
⦁ Facial flushing
⦁ Nasal congestion
⦁ Back pain
⦁ Upset stomach
⦁ Muscle discomfort
⦁ Vision alterations, including blurred vision and changes in color perception
Tadalafil
Tadalafil, known as Cialis, is an oral medication that enhances blood circulation.
You have flexibility with this PDE5 inhibitor. You can take a higher dose about 30 minutes before sexual activity, not exceeding once per day. Alternatively, opt for a lower daily dose that prepares you for sex without planning. Its effects can last for up to 36 hours.
Price for tadalafil
Tadalafil comes in both brand name Cialis and generic versions.
Choosing a higher as-needed dose might mean a higher cost per pill. Conversely, a lower daily dose may be more cost-effective per pill, but expenses can accumulate when buying a full month’s supply.
As of September 2022, generic daily 5 mg tadalafil could be around $8 per dose. Generic tadalafil in higher doses of 10 mg and 20 mg could start at approximately $44 per pill.
Common tadalafil side effects
⦁ Headache
⦁ Facial flushing
⦁ Nasal congestion
⦁ Back pain
⦁ Upset stomach
⦁ Limb discomfort
Testosterone
Testosterone is the primary male sex hormone, serving various functions in overall health.
Natural testosterone levels decline with age, leading to issues like ED, fatigue, low sex drive, weight gain, and reduced sperm count.
Doctors may prescribe testosterone to address ED. PDE5 inhibitors can be most effective when combined with testosterone therapy for individuals with testosterone deficiencies. However, testosterone treatment comes with risks.
Testosterone increases the risk of heart attacks and strokes. Due to these risks, the FDATrusted Source suggests testosterone use only for individuals with low testosterone due to specific health conditions.
Close monitoring is crucial when using testosterone. Doctors will assess your testosterone levels before and during treatment. If levels become too high, treatment may be adjusted or stopped.
Price for testosterone
Testosterone treatment options include gels, creams, capsules, and implants. Prices can vary widely among these forms. If considering testosterone therapy for ED, discuss costs and suitable options with your doctor to align with your budget.
Possible side effects of testosterone
⦁ acne
⦁ male breasts
⦁ prostate growth
⦁ fluid retention that causes swelling
⦁ moodiness
⦁ sleep apnea, or interrupted breathing during your sleep
Testosterone for ED comes in many forms. The table below lists the forms of testosterone and their brand name versions. Some forms may also be available as generic drugs.
Vardenafil
Vardenafil, available as Levitra and Staxyn, is an oral medication and PDE5 inhibitor. While Levitra comes as a conventional oral tablet, Staxyn is a disintegrating tablet that dissolves under the tongue. This unique form of medication absorption in Staxyn leads to higher systemic exposure compared to Levitra. Both forms of vardenafil require a prescription.
Take it as needed, about 60 minutes before sexual activity, although it might start working for some in around 30 minutes. This medication can be taken once per day and remains effective for approximately 5 to 7 hours.
Price for vardenafil
The cost of vardenafil can significantly vary depending on the pharmacy and even the state of purchase. As a general guideline, prices range between $78 to $150 for ten 20 mg tablets, as per GoodRx.
Vitamins and Supplements for ED
Vitamins and supplements often claim to address ED and enhance sexual function, energy, and vitality. However, these claims are usually unsupported and potentially unsafe. Some supplements might contain hidden drugs and can interact with other medications, leading to side effects.
Before considering any vitamins or supplements for ED, it’s crucial to consult your doctor to ensure safety and effectiveness.
Getting Erectile Dysfunction Medications
The most reliable source for ED medications is your doctor or a licensed medical professional. While some online pharmacies offer ED drugs, these sources lack regulation and could contain ineffective or harmful ingredients.
Cost of Erectile Dysfunction Medications
The pricing of ED medications can vary. Opting for subscription services like Hims or Roman can save costs through multi-month shipments. With or without insurance, pharmacy prices can differ, and online coupons may help reduce costs.
For instance, the average cost of a single Viagra pill is $70, while the generic sildenafil version can be as affordable as $9 per pill. Researching available services can help you find economical options.
FAQs about ED Medications
How Effective are ED Pills?
ED medications, like sildenafil, have different effectiveness levels. Sildenafil, being the longest-standing option, is often a doctor’s first choice due to its well-known side effects. However, addressing underlying causes alongside medication can be beneficial. It’s important to note that some people experience side effects, such as headaches, and medication might not be necessary for all cases of ED.
How Fast Do ED Pills Work?
Most ED medications start working within 15 to 45 minutes. Sildenafil takes 30 minutes to an hour, with effects lasting 1 to 4 hours. Cialis can take up to 2 hours to become effective and remains active for 36 hours. A daily Cialis regimen is also available.
What are ED Pills Side Effects
ED pills may lead to various side effects, ranging from mild to serious. Common mild side effects encompass headaches, warmth in the chest or face, a stuffy nose, and even nausea or diarrhea.
However, severe side effects include issues like back pain, hearing loss, ear ringing, and difficulty distinguishing between green and blue colors. Individuals with underlying health conditions, such as liver or kidney disease, and those with high blood pressure, especially if uncontrolled, should exercise caution or consult a doctor before using ED medications. Mixing nitrate drugs with ED meds is also potentially risky.
What is the best and most Effective ED Medication?
When comparing ED medications, consider personal preferences. Factors like cost, duration of effectiveness, ease of use, and the need for one-time or ongoing treatment matter. Generic versions of sildenafil, vardenafil, and tadalafil are available, accessible through subscription services like Hims or Roman.
Which is better, Viagra or Other ED Options?
Viagra is a common choice as the first ED medication, but efficacy varies among individuals. Lifestyle and preferences also play a role in medication selection. Cialis may offer longer effects, while newer drugs like Stendra might present fewer side effects. However, individuals taking nitrate medications should avoid ED pills.
When to Seek Medical Help
If experiencing ED symptoms, it’s wise to consult a healthcare provider. Persistent erection issues, reduced sexual desire, or concerns affecting relationships should prompt seeking medical advice. If ED symptoms coincide with other alarming signs like chest pain or breathlessness, immediate attention is crucial.
In Summary
ED can impact self-esteem and relationships, often originating from underlying health issues. Several approved treatments are available, each with unique forms and effects. Selecting a medication based on cost and convenience is a sensible starting point.
Always consult a physician, especially if you have existing health conditions or take other medications. While these medications can be beneficial, they might also entail rare but serious side effects.
ED is a common concern with various treatments. Consider personal factors, consult a doctor, and stay informed about potential side effects for a safe and effective approach to managing ED.